- 专利标题： PHARMACEUTICAL PREPARATION HAVING EXCELLENT DISSOLUTION PROPERTIES, CONTAINING ESOMEPRAZOLE AND SODIUM BICARBONATE
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申请号： US17270263申请日： 2019-07-26
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公开(公告)号： US20220233514A1公开(公告)日： 2022-07-28
- 发明人: Jong Seo Choi , Min Soo Kim , Shin Jung Park , Jong Lae Lim
- 申请人： CHONG KUN DANG PHARMACEUTICAL CORP.
- 申请人地址： KR Seoul
- 专利权人： CHONG KUN DANG PHARMACEUTICAL CORP.
- 当前专利权人： CHONG KUN DANG PHARMACEUTICAL CORP.
- 当前专利权人地址： KR Seoul
- 优先权： KR10-2018-0098744 20180823
- 国际申请： PCT/KR2019/009371 WO 20190726
- 主分类号： A61K31/4439
- IPC分类号： A61K31/4439 ; A61K9/16 ; A61K9/50 ; A61K9/20 ; A61K9/28
摘要：
The present invention relates to a pharmaceutical preparation comprising omeprazole, an enantiomer thereof or a pharmaceutically acceptable salt thereof, and sodium bicarbonate, and a method for preparing the same. Specifically, the present invention relates to a pharmaceutical preparation in which sodium bicarbonate is first disintegrated so as to raise pH, and then omeprazole is dissolved such that the release properties of an active ingredient are improved, and thus the dissolution pattern and bioavailability of a drug can be enhanced.
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