Invention Application
- Patent Title: PHARMACEUTICAL COMPOSITION CONTAINING STABILIZED NUCLEIC ACID ADJUVANT
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Application No.: US17617000Application Date: 2020-05-25
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Publication No.: US20220233700A1Publication Date: 2022-07-28
- Inventor: Jae Hwan NAM , Gyo Chang KEUM , Hyo Jung PARK , Eun Kyoung BANG , Hae Li KO
- Applicant: THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION , KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
- Applicant Address: KR Seoul; KR Seoul
- Assignee: THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION,KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
- Current Assignee: THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION,KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
- Current Assignee Address: KR Seoul; KR Seoul
- Priority: KR10-2019-0067129 20190607
- International Application: PCT/KR2020/006952 WO 20200525
- Main IPC: A61K47/24
- IPC: A61K47/24 ; A61K39/39 ; A61K39/215 ; C12N7/00 ; C12N15/86 ; A61K39/145 ; A61P31/16 ; A61K39/12 ; A61P31/14

Abstract:
The present disclosure relates to a pharmaceutical composition comprising a nucleic acid molecule of an adjuvant, a metal complex stabilizing the nucleic acid molecule, and optionally an immunogen that may be a peptide or a protein, or a composition of stabilizing the nucleic acid molecule of the adjuvant comprising the metal complex. The metal complex interacts with the nucleic acid molecule of the adjuvant and/or the immunogen so as to stabilize such pharmaceutically active ingredients, and induces continuous effectiveness of the active ingredients without degradation.
Information query
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