Invention Application
- Patent Title: PYRIDOPYRIMIDINES DERIVATIVES AS P2X3 INHIBITORS
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Application No.: US17615012Application Date: 2020-05-28
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Publication No.: US20220235060A1Publication Date: 2022-07-28
- Inventor: Paolo BRUNO , Matteo BIAGETTI , Claudio FIORELLI , Charles BAKER-GLENN , Hervè VAN DE POËL , Stephen David PENROSE , Roberta LANARO
- Applicant: CHIESI FARMACEUTICI S.p.A.
- Applicant Address: IT Parma
- Assignee: CHIESI FARMACEUTICI S.p.A.
- Current Assignee: CHIESI FARMACEUTICI S.p.A.
- Current Assignee Address: IT Parma
- Priority: EP19177610.3 20190531,EP19201165.8 20191002
- International Application: PCT/EP2020/064915 WO 20200528
- Main IPC: C07D487/04
- IPC: C07D487/04 ; C07D471/04
Abstract:
The present invention relates to compounds of formula I inhibiting P2X purinoceptor 3 (hereinafter P2X3 inhibitors); particularly the invention relates to compounds that are pyridopyrimidines derivatives, methods of preparing such compounds, pharmaceutical compositions containing them and therapeutic use thereof. The compounds of the invention may be useful in the treatment of many disorders associated with P2X3 receptors mechanisms, such as respiratory diseases including cough, asthma, idiopathic pulmonary fibrosis (IPF) and chronic obstructive pulmonary disease (COPD).
Public/Granted literature
- US20230212169A9 PYRIDOPYRIMIDINES DERIVATIVES AS P2X3 INHIBITORS Public/Granted day:2023-07-06
Information query
