In embodiments of efficient network stack for wireless application protocols, a network stack receives an application-layer message in a first wireless application protocol that includes a source address and a destination address, maps the source address to an Internet Protocol version 6 (IPv6) source address, and maps the destination address to an IPv6 source address. The source node transmits the application-layer message to a destination node in a mesh network using a network stack that implements a second wireless application protocol using the IPv6 source address, and maps the destination address to an IPv6 source address.