Invention Application
- Patent Title: Lipid Particle Formulations for Delivery of RNA and Water-Soluble Therapeutically Effective Compounds to a Target Cell
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Application No.: US17727956Application Date: 2022-04-25
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Publication No.: US20220249372A1Publication Date: 2022-08-11
- Inventor: Hossam Hefesha , Ugur Sahin , Heinrich Haas , Sebastian Kreiter , Yves Hüsemann , Mustafa Diken , Kerstin Walzer
- Applicant: BioNTech SE , Tron-Translationale Onkologie an der Universitatsmedizin der Johannes Gutenberg-University Mainz Gmb
- Applicant Address: DE Mainz; DE Mainz
- Assignee: BioNTech SE,Tron-Translationale Onkologie an der Universitatsmedizin der Johannes Gutenberg-University Mainz Gmb
- Current Assignee: BioNTech SE,Tron-Translationale Onkologie an der Universitatsmedizin der Johannes Gutenberg-University Mainz Gmb
- Current Assignee Address: DE Mainz; DE Mainz
- Main IPC: A61K9/107
- IPC: A61K9/107 ; A61K9/127 ; A61K48/00 ; A61K31/675 ; A61K31/7105 ; A61K9/00 ; A61K31/663 ; A61K45/06 ; A61K39/395 ; A61P35/00 ; A61K39/00 ; A61K47/18 ; A61K47/24
Abstract:
The present invention relates to lipid particles comprising at least one cationic lipid, at least one water-soluble therapeutically effective compound and RNA. Further, the present invention relates to a pharmaceutical composition comprising such particles. Said pharmaceutical composition is useful for inducing an immune response. It is also useful in a prophylactic and/or therapeutic treatment of a disease involving an antigen. Furthermore, the present invention relates to a method for producing the particles.
Information query
