Invention Application
- Patent Title: CF3-, OCF3-, SCF3-, and SF5-Containing Antibacterial Agents
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Application No.: US17606720Application Date: 2020-04-24
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Publication No.: US20220249447A1Publication Date: 2022-08-11
- Inventor: Herman O. Sintim , George Naclerio
- Applicant: Purdue Research Foundation
- Applicant Address: US IN West Lafayette
- Assignee: Purdue Research Foundation
- Current Assignee: Purdue Research Foundation
- Current Assignee Address: US IN West Lafayette
- International Application: PCT/US2020/029689 WO 20200424
- Main IPC: A61K31/4245
- IPC: A61K31/4245 ; C07D413/04 ; C07D417/14 ; C07D413/14 ; C07D271/113 ; C07D409/04 ; C07D271/07 ; C07D413/12 ; C07D277/46 ; C07D231/40 ; C07D257/06 ; A61K31/427 ; A61K31/4439 ; A61K31/4196 ; A61K31/433 ; A61K31/426 ; A61K31/415 ; A61K31/41 ; A61K45/06

Abstract:
The present invention generally relates to compounds as a new antibiotic to treat various infections, including infections caused by methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-intermediate and vancomycin-resistant S. aureus (VISA and VRSA respectively) vancomycin-resistant Enterococcusfaecalis (VRE), and Clostridioides difficile. Pharmaceutical compositions and methods for treating those infection diseases are within the scope of this invention.
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