- 专利标题： CF3-, OCF3-, SCF3-, and SF5-Containing Antibacterial Agents
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申请号： US17606720申请日： 2020-04-24
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公开(公告)号： US20220249447A1公开(公告)日： 2022-08-11
- 发明人: Herman O. Sintim , George Naclerio
- 申请人： Purdue Research Foundation
- 申请人地址： US IN West Lafayette
- 专利权人： Purdue Research Foundation
- 当前专利权人： Purdue Research Foundation
- 当前专利权人地址： US IN West Lafayette
- 国际申请： PCT/US2020/029689 WO 20200424
- 主分类号： A61K31/4245
- IPC分类号： A61K31/4245 ; C07D413/04 ; C07D417/14 ; C07D413/14 ; C07D271/113 ; C07D409/04 ; C07D271/07 ; C07D413/12 ; C07D277/46 ; C07D231/40 ; C07D257/06 ; A61K31/427 ; A61K31/4439 ; A61K31/4196 ; A61K31/433 ; A61K31/426 ; A61K31/415 ; A61K31/41 ; A61K45/06
摘要：
The present invention generally relates to compounds as a new antibiotic to treat various infections, including infections caused by methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-intermediate and vancomycin-resistant S. aureus (VISA and VRSA respectively) vancomycin-resistant Enterococcusfaecalis (VRE), and Clostridioides difficile. Pharmaceutical compositions and methods for treating those infection diseases are within the scope of this invention.
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