Invention Application
![CRYSTALLINE FORMS OF 7-CHLORO-2-(4-(3-METHOXYAZETIDIN-1-YL)CYCLOHEXYL)-2,4-DIMETHYL-N-((6-METHYL-4-(METHYLTHIO)-2-OXO-1,2-DIHYDROPYRIDIN-3-YL)METHYL)BENZO[D][1,3]DIOXOLE-5-CARBOXAMIDE](/docs/US/2022-08-11/US20220251073A1/abs.jpg.600x600.jpg)
- Patent Title: CRYSTALLINE FORMS OF 7-CHLORO-2-(4-(3-METHOXYAZETIDIN-1-YL)CYCLOHEXYL)-2,4-DIMETHYL-N-((6-METHYL-4-(METHYLTHIO)-2-OXO-1,2-DIHYDROPYRIDIN-3-YL)METHYL)BENZO[D][1,3]DIOXOLE-5-CARBOXAMIDE
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Application No.: US17628947Application Date: 2020-07-23
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Publication No.: US20220251073A1Publication Date: 2022-08-11
- Inventor: Alamelu Banda , Victor S. Gehling
- Applicant: Constellation Pharmaceuticals, Inc.
- Applicant Address: US MA Cambridge
- Assignee: Constellation Pharmaceuticals, Inc.
- Current Assignee: Constellation Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- International Application: PCT/US2020/043178 WO 20200723
- Main IPC: C07D405/14
- IPC: C07D405/14
![CRYSTALLINE FORMS OF 7-CHLORO-2-(4-(3-METHOXYAZETIDIN-1-YL)CYCLOHEXYL)-2,4-DIMETHYL-N-((6-METHYL-4-(METHYLTHIO)-2-OXO-1,2-DIHYDROPYRIDIN-3-YL)METHYL)BENZO[D][1,3]DIOXOLE-5-CARBOXAMIDE](/abs-image/US/2022/08/11/US20220251073A1/abs.jpg.150x150.jpg)
Abstract:
The present disclosure relates to a crystalline Form 1 of 7-chloro-2-(4-(3-methoxyazetidin-1-yl)cyclohexyl)-2,4-di -methyl-N-((6-methyl-4-(methylthio)-2-oxo-1,2-dihydropyridin-3-yl)methyl)benzo[d] [1,3]dioxole-5-carboxamide, which is useful as modulators the activity of histone methyl modifying enzymes. The present disclosure also provides pharmaceutically acceptable compositions comprising the crystalline form and methods of using said compositions in the treatment of various disorders.
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