Maytansinoid Derivatives, Conjugates Thereof, and Methods of Use

Invention Application

US20220259225A1 Maytansinoid Derivatives, Conjugates Thereof, and Methods of Use 有权

Patent Title: Maytansinoid Derivatives, Conjugates Thereof, and Methods of Use
Application No.: US17528144

Application Date: 2021-11-16
Publication No.: US20220259225A1

Publication Date: 2022-08-18
Inventor: Thomas NITTOLI
Applicant: Regeneron Pharmaceuticals, Inc.
Applicant Address: US NY Tarrytown
Assignee: Regeneron Pharmaceuticals, Inc.
Current Assignee: Regeneron Pharmaceuticals, Inc.
Current Assignee Address: US NY Tarrytown
Main IPC: C07D498/18
IPC: C07D498/18 ; A61K47/68

Abstract:

Provided herein are maytansinoid derivatives, conjugates thereof, and methods of treating or preventing proliferative diseases with the same.

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IPC分类:

C	化学；冶金
C07	有机化学
C07D	杂环化合物（高分子化合物入C08）
C07D498/00	杂环化合物，在稠环系中至少有1个杂环具有氮和氧原子作为仅有的杂环原子（4-氧杂-1-氮杂双环〔3.2.0〕庚烷环系，例如氧代青霉素入C07D503/00；5-氧杂-1-氮杂双环〔4.2.0〕辛烷类，例如氧代头孢菌素入C07D505/00；在其他位置有环氧原子的同系物入C07D507/00）
C07D498/12	.在稠环系中含有3个杂环
C07D498/18	..桥系