Invention Application
- Patent Title: NATRIURETIC PEPTIDE RECEPTOR A AGONISTS USEFUL FOR THE TREATMENT OF CARDIOMETABOLIC DISEASES, KIDNEY DISEASE AND DIABETES
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Application No.: US17611540Application Date: 2020-05-18
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Publication No.: US20220273669A1Publication Date: 2022-09-01
- Inventor: Qingmei Hong , Jason E. Imbriglio , Angela D. Kerekes , Tanweer Khan , Claire Lankin , Derun Li , Rui Liang , Pengcheng Patrick Shao , Zhicai Wu , Yusheng Xiong , Feng Ye , Hyewon Youm , Yang Yu , Anthappan Tony Kurissery , Venukrishnan Komanduri
- Applicant: Merck Sharp & Dohme Corp.
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- International Application: PCT/US2020/033354 WO 20200518
- Main IPC: A61K31/54
- IPC: A61K31/54 ; C07D495/04 ; C07D519/00 ; C07D513/04 ; A61K31/4545 ; A61K31/438 ; A61K31/444
Abstract:
The present invention relates to Compounds of Formula I: I and pharmaceutically acceptable salts or prodrug thereof. The present invention also relates to compositions comprising at least one compound of Formula I, and methods of using the compounds of Formula I for treatment of cardiometabolic diseases including high blood pressure, heart failure, kidney disease, and diabetes in a subject.
Information query
