Systems and methods for the optimized allocation of content on a content distribution system according to a content distribution plan are described. In some embodiments, a management system may be configured to generate an optimized schedule for content distribution, such as an advertising campaign. For a television distribution schedule, an impressions forecast may be generated based on the available inventory and historical audience measurement information, such as television ratings for a television advertising campaign. An optimized schedule may be generated based on the impressions forecast and content may be distributed according to the optimized schedule. Measurement information relating to the distribution according to the optimized schedule may be analyzed and used to generate a re-optimized schedule, for example, that may be used to schedule the advertising campaign on a subsequent day.