An anchoring apparatus for a medical microdevice and a method of selectively maintaining the medical microdevice in a predetermined position within a body tissue are provided. The medical microdevice includes a body having longitudinally spaced proximal and distal device ends and a guidewire extending proximally from the proximal device end. The anchoring apparatus includes a selectively expandable anchor having longitudinally spaced proximal and distal anchor ends. A selected one of the proximal and distal anchor ends is connected to the distal or proximal device end, respectively. The anchor self-expands from a collapsed insertion condition to an expanded anchoring condition after insertion into a body tissue to resist post-implantation motion of the microdevice.