Invention Application
- Patent Title: INDOLINONE COMPOUNDS AND USES THEREOF
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Application No.: US17830668Application Date: 2022-06-02
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Publication No.: US20220288023A1Publication Date: 2022-09-15
- Inventor: Jean-Michel Vernier
- Applicant: Oncternal Therapeutics, Inc.
- Applicant Address: US CA San Diego
- Assignee: Oncternal Therapeutics, Inc.
- Current Assignee: Oncternal Therapeutics, Inc.
- Current Assignee Address: US CA San Diego
- Main IPC: A61K31/404
- IPC: A61K31/404 ; C07D401/10 ; C07D403/10 ; C07D209/34 ; C07D209/38 ; C07D401/06 ; A61K31/4155 ; A61K31/4439 ; A61K31/5377

Abstract:
Indolinone derivative compounds that act as EWS-FLI1 transcription factor inhibitors are provided. Also provided are pharmaceutical compositions of the indolinone derivatives, methods of synthesizing the same, methods of treating using same, and assays for identifying the inhibitors of EWS-FLI1 oncoprotein.
Information query
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