- 专利标题： ASH1L INHIBITORS AND METHODS OF TREATMENT THEREWITH
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申请号： US17504159申请日： 2021-10-18
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公开(公告)号： US20220288217A1公开(公告)日： 2022-09-15
- 发明人: Jolanta Grembecka , Szymon Klossowski , Jing Deng , Tomasz Cierpicki , Hao Li , Hongzhi Miao , Trupta Purohit , EunGi Kim
- 申请人： The Regents of the University of Michigan
- 申请人地址： US MI Ann Arbor
- 专利权人： The Regents of the University of Michigan
- 当前专利权人： The Regents of the University of Michigan
- 当前专利权人地址： US MI Ann Arbor
- 主分类号： A61K47/64
- IPC分类号： A61K47/64 ; A61K9/00 ; A61K31/454 ; A61K38/45 ; A61P35/02 ; A61K47/54 ; A61K31/404 ; A61K31/4545 ; C07D209/24 ; C07D471/04
摘要：
Provided herein are small molecules that bind to ASH1L and inhibit ASH1L activity, and methods of use thereof for the treatment of disease, including acute leukemia, solid cancers and other diseases dependent on activity of ASH1L.
公开/授权文献
- US11833210B2 ASH1L inhibitors and methods of treatment therewith 公开/授权日：2023-12-05
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