- 专利标题： METHODS TO DETECT MOTOR NEURON DISEASE COMPRISING MICRO-RNAs
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申请号： US17575410申请日： 2022-01-13
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公开(公告)号： US20220290138A1公开(公告)日： 2022-09-15
- 发明人: Timothy M. Miller , Mariah Lawler Hoye , Ted Hyman , Erica Koval , Joseph Dougherty
- 申请人： Washington University
- 申请人地址： US MO St. Louis
- 专利权人： Washington University
- 当前专利权人： Washington University
- 当前专利权人地址： US MO St. Louis
- 主分类号： C12N15/113
- IPC分类号： C12N15/113 ; A61P25/28 ; A61K31/7105 ; C12N15/11 ; C12Q1/6883
摘要：
The present invention relates to compositions and methods for detecting motor neuron-specific miRNAs in a population of cells or subject. More particularly, the invention relates to detecting motor neuron-specific miRNAs to detect and treat motor neuron diseases associated with dysregulation of motor neuron-specific miRNAs, such as Amyotrophic Lateral Sclerosis (ALS).
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