A touch screen protective film structure with a penetrating-transmitting signal function includes a touch screen protective film and at least one signal transmission path. The at least one signal transmission path is embedded in the touch screen protective film partially or completely. The at least one signal transmission path includes a first end and a second end. The second end faces a specific touch area of a touch screen of an electronic apparatus. The first end receives a touch signal and transmits the touch signal to the second end. The specific touch area senses the touch signal to operate the electronic apparatus based on the touch signal. The second end defines at least one gap. The specific touch area penetrates the at least one gap defined by the second end to be touched for operating the electronic apparatus.