Invention Application
- Patent Title: TRANS-ANETHOLE ((E)-1-METHOXY-4- (1-PROPENYL) BENZENE), A NEW AND POTENT INHIBITOR OF PROLYL ENDOPEPTIDASE
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Application No.: US17214886Application Date: 2021-03-28
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Publication No.: US20220304946A1Publication Date: 2022-09-29
- Inventor: Muhammad Imran Khan , Depeng Wang , Najeeb Ullah , Fawad Ali Shah , Shah Fahad , Shahid Ullah Khan , Abdul Wahab , Arif Ullah Khan
- Applicant: Muhammad Imran Khan , Depeng Wang , Najeeb Ullah , Fawad Ali Shah , Shah Fahad , Shahid Ullah Khan , Abdul Wahab , Arif Ullah Khan
- Applicant Address: PK Islamabad; CN Linyl; PK Peshawa; PK Islamabad; PK Haripur; CN Guanshan; PK Kohat; PK Islamabad
- Assignee: Muhammad Imran Khan,Depeng Wang,Najeeb Ullah,Fawad Ali Shah,Shah Fahad,Shahid Ullah Khan,Abdul Wahab,Arif Ullah Khan
- Current Assignee: Muhammad Imran Khan,Depeng Wang,Najeeb Ullah,Fawad Ali Shah,Shah Fahad,Shahid Ullah Khan,Abdul Wahab,Arif Ullah Khan
- Current Assignee Address: PK Islamabad; CN Linyl; PK Peshawa; PK Islamabad; PK Haripur; CN Guanshan; PK Kohat; PK Islamabad
- Main IPC: A61K31/085
- IPC: A61K31/085 ; A61K45/06
Abstract:
Overexpression of prolyl endopeptidase (PEP) activity in the brain was found to be linked with neurodegenerative disorders, and the memory loss caused by amnesic compounds can be restored by PEP inhibitors. In the current intervention, the PEP inhibitory activity of trans-anethole ((E)-1-Methoxy-4-(1-propenyl)benzene), an essential oil that is naturally occurring in Illicium verum (star anise) has been assessed. More specifically, the present invention relates to finding of a potent inhibitor of prolyl endopeptidase (Trans-Anethole ((E)-1-Methoxy-4-(1-propenyl)benzene).
Information query
