发明申请
- 专利标题： Compositions and Methods for Producing High Secreted Yields of Recombinant Proteins
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申请号： US17751277申请日： 2022-05-23
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公开(公告)号： US20220306706A1公开(公告)日： 2022-09-29
- 发明人: Joshua Kittleson , Thomas Stevens , Rena Hill , Carlos Gustavo Pesce
- 申请人： BOLT THREADS, INC.
- 申请人地址： US CA Emeryville
- 专利权人： BOLT THREADS, INC.
- 当前专利权人： BOLT THREADS, INC.
- 当前专利权人地址： US CA Emeryville
- 主分类号： C07K14/435
- IPC分类号： C07K14/435 ; C07K14/395 ; C12N15/81 ; C12P21/02 ; C12N15/62
摘要：
The present disclosure relates to methods for producing recombinant proteins, as well as compositions used in and produced by such methods. Specifically, the present disclosure relates to methods for producing high secreted yields of recombinant proteins, and the compositions provided herein include recombinant host cells that comprise polynucleotide sequences encoding proteins operably linked to at least 2 distinct secretion signals.
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