A computer vision-based anomaly detection method and device and an electronic apparatus are disclosed. The method comprises: dividing a target picture into at least two feature regions according to different region features of the target picture, and forming training sets respectively using the feature regions corresponding to each target picture; selecting generative adversarial networks GAN as network models to be used, and training GAN network models with the training sets of different feature regions to obtain GAN network models corresponding to different feature regions; and when performing anomaly detection, performing same feature region division on a target picture to be detected, inputting different feature regions of the target picture to be detected into corresponding GAN network models to obtain a generated picture, and performing pixel value-based difference detection on the generated picture and the target picture to be detected.