A device for axial and rotational locking of a dual catheter system and methods of the same. The system includes an outer catheter and an inner catheter adapted to be inserted into the outer catheter. The outer catheter extends along a catheter axis and includes an outer catheter shaft and an outer catheter hub. The inner catheter includes an inner catheter shaft and an inner catheter hub. The system also includes an intermediate hub located between the inner and outer catheters. The intermediate hub includes a deformable component positioned around at least a portion of the inner catheter. The deformable component is adapted to be inserted into the outer catheter hub such that the inner catheter is restricted, rotationally about and axially along the catheter axis, relative to the outer catheter.