A tire pressure monitoring module of a vehicle, a tire localization system and a tire localization method of a vehicle are provided. Each of tires is determined to be a left tire or a right tire based on a phase relationship of components of magnetic field intensity in two different directions in the tire. The components of magnetic field intensity in two different directions are measured by a magnetometer in the tire pressure monitoring module. The tire is determined to be a front tire or a right tire based on magnitude of an AOA of a first Bluetooth module in the tire pressure monitoring module relative to a multi-antenna Bluetooth host. In this way, the tires of the vehicle are positioned automatically with a high precision. In addition, the tire pressure monitoring module may be mounted on any tire without any distinction, which reduces the installation cost.