- 专利标题： ANTIBODIES AGAINST HUMAN TREM-1 AND USES THEREOF
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申请号： US17627085申请日： 2020-07-15
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公开(公告)号： US20220332817A1公开(公告)日： 2022-10-20
- 发明人: Achal M. PASHINE , Joseph TOTH , Ginger C. RAKESTRAW
- 申请人： BRISTOL-MYERS SQUIBB COMPANY
- 申请人地址： US NJ Princeton
- 专利权人： BRISTOL-MYERS SQUIBB COMPANY
- 当前专利权人： BRISTOL-MYERS SQUIBB COMPANY
- 当前专利权人地址： US NJ Princeton
- 国际申请： PCT/US2020/042172 WO 20200715
- 主分类号： C07K16/28
- IPC分类号： C07K16/28 ; A61P29/00 ; A61P37/00 ; C12N15/63
摘要：
Provided herein are antibodies, or antigen-binding portions thereof, that specifically bind and inhibit TREM-1 signaling. Also provided are uses of such antibodies, or antigen-binding portions thereof, in therapeutic applications, such as treatment of autoimmune diseases.
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