The present disclosure provides a display substrate and a display device. The display substrate includes: a gate driving circuitry arranged at a peripheral region of the display substrate; n clock signal leads coupled to the gate driving circuitry, each clock signal lead extending in a first direction; and n clock signal lines arranged sequentially in the first direction, each clock signal line extending in a second direction intersecting the first direction, where n is a positive integer greater than 1. The clock signal leads have a same length in the first direction, each clock signal lead extends from a first clock signal line to an nth clock signal line, and each clock signal lead is coupled to a corresponding clock signal line at a position where the clock signal lead intersects the clock signal line.