An electronic device includes at least one hardware element, a wireless communication circuit that supports time division duplexing (TDD) communication, a plurality of antennas, a processor, and a memory storing reference strength information. The processor may be configured to identify a victim in operation in the at least one hardware element, and identify at least one first antenna operating as an aggressor against the victim in the plurality of antennas. When the at least one first antenna transmits a wireless signal, the processor may be configured to identify a ratio of uplink symbols for a specified time period, identify a first reference strength based on the ratio, identify a second reference strength based on the reference strength information, and transmit the wireless signal based on a result of comparing the first reference strength with the second reference strength.