- 专利标题： Anti-CD39 Antibody Compositions and Methods
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申请号： US17642824申请日： 2020-09-15
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公开(公告)号： US20220372160A1公开(公告)日： 2022-11-24
- 发明人: Scott CHAPPEL , Andrew LAKE , Michael WARREN , Austin DULAK , Erik DEVEREAUX , Pamela M. HOLLAND , Tauqeer ZAIDI , Matthew RAUSCH , Bianka Prinz , Nels P. NIELSON , Sonia DAS , Alison M. O'Neill
- 申请人： Surface Oncology, Inc.
- 申请人地址： US MA Cambridge
- 专利权人： Surface Oncology, Inc.
- 当前专利权人： Surface Oncology, Inc.
- 当前专利权人地址： US MA Cambridge
- 国际申请： PCT/US2020/050829 WO 20200915
- 主分类号： C07K16/28
- IPC分类号： C07K16/28 ; A61P35/00
摘要：
The invention provides anti-CD39 antibody compositions and their use in treating cancer. In some embodiments, an isolated anti-CD39 antibody is provided. Such an isolated anti-CD39 antibody binds to human CD39, wherein the antibody is optionally fully human or humanized. In some embodiments, the disclosure provides a method of enhancing, increasing and/or sustaining an anti-tumor immune response in a subject comprising administering the antibody or composition described herein to a subject having a tumor.
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