A process fluid connector for a single-use process fluid sensing system is provided. The process fluid connector includes a pair of process fluid connections, each process fluid connection being configured to couple to a cooperative process fluid coupling. A process fluid conduit section is operably coupled to each of the process fluid connections. A sensor attachment port is coupled to the process fluid conduit section and is configured to receive and mount a process fluid sensor. A retractable fluid chamber is coupled to the process fluid conduit section and configured to provides wet storage for sensing component(s) of the process fluid sensor. A process fluid sensing system using the process fluid connector is also provided.