- 专利标题： 2, 4, 6-TRI-SUBSTITUTED PYRIMIDINE COMPOUND AS ATR KINASE INHIBITOR
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申请号： US17616571申请日： 2020-06-05
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公开(公告)号： US20220378799A1公开(公告)日： 2022-12-01
- 发明人: Yanping Zhao , Hongjun Wang , Bin Liu , Yuanyuan Jiang , Weiting Zhong , Huifen Xu , Honglei Zhang , Chuangchuang Huang , Nana Tian , Jing Zhao , Jing Li , Weina Liu , Liying Zhou , Yanan Liu
- 申请人： BEIJING TIDE PHARMACEUTICAL CO., LTD.
- 申请人地址： CN Beijing
- 专利权人： BEIJING TIDE PHARMACEUTICAL CO., LTD.
- 当前专利权人： BEIJING TIDE PHARMACEUTICAL CO., LTD.
- 当前专利权人地址： CN Beijing
- 优先权： CN201910490080.6 20190606,CN201910876919.X 20190917,CN202010441539.6 20200522
- 国际申请： PCT/CN2020/094532 WO 20200605
- 主分类号： A61K31/5377
- IPC分类号： A61K31/5377 ; C07D471/04 ; C07D413/14 ; A61P35/00
摘要：
Compounds of general formula (A) can be used for treating ATR kinase-mediated diseases, for example, hyperplastic diseases such as cancers. Also provided are a pharmaceutical composition of the compounds of general formula (A), a use of the pharmaceutical composition for treating the ATR kinase-mediated diseases and a preparation method for the pharmaceutical composition.
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