An approach to workflow management in response to a detected security incident in a computer system. The approach may include an inference driven response based on prior artifacts. The inference driven response may predict the condition of the system and the outcomes of actions in response to the security incident. The predictions made by the inference drive response may be based on a machine learning model. The inference driven response may pause or prevent scheduled actions of the system based on the predictions. The inference driven response may continue to monitor the system and dynamically update its predictions for the condition of the system. In response to the updated predictions, the inference driven response may cancel or execute the previously scheduled actions of the system.