According to various embodiments, a wearable electronic device comprises a memory, a first sensor, a second sensor, and a processor, wherein the processor may be configured to, obtain a user's first biometric signal in a user's first posture through the first sensor, obtain, from an external electronic device, information about the user's first blood pressure value measured by the external electronic device in the first posture, obtain first calibration information for quantifying first blood pressure information measured in the first posture, based on information about features of the first biometric signal and the first blood pressure value, identify whether calibration data sets for a plurality of postures of the user, pre-stored in the memory, meet a specific condition for estimating second calibration information for quantifying second blood pressure information measured in the user's second posture, and when the calibration data sets meet the specific condition, estimate the second calibration information based on the calibration data sets and the first calibration information.