An aircraft includes a fuselage airframe and a wing airframe that is subject to flight loads. The fuselage airframe includes fore/aft floor beams having a plurality of floor intercostals laterally extending therebetween and fore/aft roof beams with a plurality of roof intercostals laterally extending therebetween. Each of a plurality of cabin frames extends generally vertically between respective floor and roof beams. The wing airframe includes forward and aft wing spars with a plurality of wing ribs extending therebetween. At least one fuel tank, that is configured to contain a pressurized fuel such as pressurized hydrogen fuel, integrally forms at least a portion of one of the beams, the intercostals, the frames, the spars and/or the ribs such that the fuel tank is subject to the flight loads.