- 专利标题: Adalimumab Variants with Reduced Immunogenic Potential
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申请号: US17786206申请日: 2020-12-17
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公开(公告)号: US20230142800A1公开(公告)日: 2023-05-11
- 发明人: Hervé Nozach , Coline Sivelle , Raphaël Sierocki , Bernard Maillere
- 申请人: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
- 申请人地址: FR Paris
- 专利权人: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
- 当前专利权人: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
- 当前专利权人地址: FR Paris
- 优先权: FR 1914645 2019.12.17
- 国际申请: PCT/FR2020/052485 2020.12.17
- 进入国家日期: 2022-12-05
- 主分类号: C07K16/24
- IPC分类号: C07K16/24 ; A61P37/02
摘要:
The invention relates to adalimumab variants with reduced immunogenic potential and retained or increased affinity and therapeutic applications thereof.
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