Invention Publication
- Patent Title: 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 13 INHIBITORS AND METHODS OF USE THEREOF
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Application No.: US17891436Application Date: 2022-08-19
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Publication No.: US20230143250A1Publication Date: 2023-05-11
- Inventor: Guoqiang Wang , Jun Ma , Brett Granger , Jiang Long , Bin Wang , Sourav Ghorai , Jing He , Yong He , Xuechao Xing , Ruichao Shen , Yat Sun Or
- Applicant: Enanta Pharmaceuticals, Inc.
- Applicant Address: US MA Watertown
- Assignee: Enanta Pharmaceuticals, Inc.
- Current Assignee: Enanta Pharmaceuticals, Inc.
- Current Assignee Address: US MA Watertown
- Main IPC: C07D265/36
- IPC: C07D265/36 ; C07D277/36 ; C07C311/29 ; C07D217/20 ; C07D471/04 ; C07D209/18 ; C07D209/44 ; C07D417/12 ; C07D417/04 ; C07D307/81
Abstract:
The present invention provides compounds of Formula (I),
pharmaceutical compositions comprising these compounds and methods of using these compounds to provides a method of modulating a HSD17B13 protein for treatment of metabolic disease or liver condition, The present invention relates generally to compounds and pharmaceutical compositions useful as 17β-HSD13 inhibitors. Specifically, the present invention relates to compounds useful as inhibitors of 17β-HSD13 and methods for their preparation and use.
pharmaceutical compositions comprising these compounds and methods of using these compounds to provides a method of modulating a HSD17B13 protein for treatment of metabolic disease or liver condition, The present invention relates generally to compounds and pharmaceutical compositions useful as 17β-HSD13 inhibitors. Specifically, the present invention relates to compounds useful as inhibitors of 17β-HSD13 and methods for their preparation and use.
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