- 专利标题： TRICYCLIC COMPOUNDS AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS
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申请号： US17964491申请日： 2022-10-12
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公开(公告)号： US20230146535A1公开(公告)日： 2023-05-11
- 发明人: Thomas Allen Chappie , Nandini Chaturbhai Patel , Patrick Robert Verhoest , Christopher John Helal , Simone Sciabola , Erik Alphie LaChapelle , Travis T. Wager , Ramalakshmi Yegna Chandrasekaran
- 申请人： PFIZER INC.
- 申请人地址： US NY NEW YORK
- 专利权人： PFIZER INC.
- 当前专利权人： PFIZER INC.
- 当前专利权人地址： US NY NEW YORK
- 主分类号： C07D471/14
- IPC分类号： C07D471/14 ; C07D491/147 ; C07D491/22 ; C07D513/14 ; C07D519/00 ; C07D487/04 ; C07D487/14 ; C07D498/22 ; C07D471/22
摘要：
The present invention is directed to compounds of Formula I: or a pharmaceutically acceptable salt thereof, wherein the substituents A, R1, R2, R3a, R3b, R4a, R4b and n are as defined herein. The inventions also directed to pharmaceutical compositions comprising the compounds, methods of treatment using the compounds and methods of preparing the compounds.
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