Systems and methods for migrating users and modifying workspace definitions of persona groups are described. In some embodiments, a memory storage device may have program instructions stored thereon that, upon execution by a workspace orchestration service, cause the service to: distribute a first workspace definition based upon a first persona group associated with a user to a client device operated by the user, where the user IHS is configured to instantiate a first workspace based upon the first workspace definition; and in response to a change in a productivity or security metric of the first workspace, determine whether to: (a) migrate the user to an existing second persona group, (b) create a third persona group and migrate the user to the third persona group, (c) modify the first persona group and migrate the user to the modified first persona group, or (d) identify a potential security threat.