The present disclosure relates to a method for operating a medical imaging system (100), the method carried out by use of a data processing unit (120), the method comprising: obtaining (SI), by a computational prediction model, time-invariant patient information, generating (S2), by the computational prediction model, a patient profile parametrized based on at least the obtained time-invariant patient information, obtaining (S3), by the computational prediction model, at least one current clinical workflow parameter, providing (S4), by the computational prediction model, a prediction comprising at least a patient-specific operation workflow based on at least correlating the generated patient profile with the obtained current clinical workflow parameter, wherein the patient-specific operation workflow comprises a specific one of a selection of operational modes of the medical imaging system, and operating the medical imaging system (100) based on the specific one of the selection of operational modes.