Methods and systems for providing computer-assisted guided review of unstructured data to generate a structured data output based on customizable template rules are provided. In embodiments, an unstructured file is received, and a predefined template is selected. The predefined template includes a plurality of fields, each field corresponding to a field of the structured report. The predefined template also defines extraction rules for each field of the predefined template, and the extraction rules define parameters for identifying unstructured data relevant to the associated field. The extraction rules are applied to the unstructured file to identify data relevant to the field associated with the corresponding extraction rule, and the data identified as relevant is confirmed. Confirming the relevant data includes determining to refine the relevant data based on a condition, and modifying the extraction rule associated with the field to refine the relevant data.