Invention Application
- Patent Title: MACROCYCLIC COMPOUNDS AND USES THEREOF
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Application No.: US17808418Application Date: 2022-06-23
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Publication No.: US20230016686A1Publication Date: 2023-01-19
- Inventor: Yoshito Kishi , Kazunobu Kira , Ken Ito
- Applicant: President and Fellows of Harvard College , Eisai R&D Management Co., LTD.
- Applicant Address: US MA Cambridge; JP Tokyo
- Assignee: President and Fellows of Harvard College,Eisai R&D Management Co., LTD.
- Current Assignee: President and Fellows of Harvard College,Eisai R&D Management Co., LTD.
- Current Assignee Address: US MA Cambridge; JP Tokyo
- Main IPC: C07D493/22
- IPC: C07D493/22 ; A61P35/04

Abstract:
The present invention provides novel compounds (e.g., compounds of Formulae (I), (II), (III), (IV)) having tumor vascular remodeling effect and/or anti-CAF (Cancer Associated Fibroblasts) activity, or pharmaceutically acceptable salts thereof, optionally in a pharmaceutically acceptable carrier, and a medical uses thereof.
Public/Granted literature
- US11814398B2 Macrocyclic compounds and uses thereof Public/Granted day:2023-11-14
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