The present invention relates to nanofilters and nanofliter systems for personal and health care protective equipment to protect against health and safety hazards having application in healthcare, industrial, public, domestic environments, They are applied to face masks, respirators, face shields, protective glasses and clothes, to protect healthcare workers and other individuals against microparticles, dust, bacteria, fumes, vapors, gases, allergens, air pollutants, airborne microorganisms and especially nanosized viruses such as influenza, HIV, SARs, SARs-CoV-2. It also relates to a method for fabricating thereof with higher filtration efficiency, and to Nano-face masks, respirators, Nano-face shields exhibiting antibacterial, anti-viral protection and particulate-filtering due to the excellent barrier and filtration properties of the nanofliter system. It is also applied to the delivery of nanoparticles, organic or inorganic with antibacterial, antiviral properties, drugs, therapeutic agents, nanomedicines, or/and compounds, sensors,