Invention Publication
- Patent Title: IMPROVED MRNA-LOADED LIPID NANOPARTICLES AND PROCESSES OF MAKING THE SAME
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Application No.: US17625507Application Date: 2020-07-08
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Publication No.: US20230181483A1Publication Date: 2023-06-15
- Inventor: Shrirang Karve , Ashish Sarode , Frank DeRosa
- Applicant: Translate Bio, Inc.
- Applicant Address: US MA Lexington
- Assignee: Translate Bio, Inc.
- Current Assignee: Translate Bio, Inc.
- Current Assignee Address: US MA Lexington
- International Application: PCT/US2020/041122 2020.07.08
- Date entered country: 2022-01-07
- Main IPC: A61K9/51
- IPC: A61K9/51 ; A61K47/54 ; A61K47/69 ; A61K9/00 ; A61K9/127

Abstract:
The present invention provides an improved lipid nanoparticle formulation encapsulating mRNA comprising DEPE as a helper lipid.
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