Invention Publication
- Patent Title: IMPROVED SYNTHESIS OF KRAS G12C INHIBITOR COMPOUND
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Application No.: US17776950Application Date: 2020-11-13
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Publication No.: US20230192682A1Publication Date: 2023-06-22
- Inventor: Michael Thomas CORBETT , Sebastien CAILLE
- Applicant: AMGEN INC.
- Applicant Address: US CA Thousand Oaks
- Assignee: AMGEN INC.
- Current Assignee: AMGEN INC.
- Current Assignee Address: US CA Thousand Oaks
- International Application: PCT/US2020/060415 2020.11.13
- Date entered country: 2022-05-13
- Main IPC: C07D471/04
- IPC: C07D471/04 ; C07D213/73
Abstract:
The present disclosure relates to an improved, efficient, scalable process to prepare intermediate compounds, such as 2-isopropyl-4-methylpyridin-3-amine, useful for the synthesis of compounds, such as Compound 9, for the treatment of KRAS G12C mutated cancers.
Information query
