A method and a system for generating a dynamic addictive neural circuit based on weakly supervised contrastive learning are disclosed. The method includes: based on a convolutional neural network, reducing a dimensionality of voxels of multiple groups of fMRI to attributes of brain region nodes, and generating multiple groups of dynamic brain connection maps containing time series based on the attributes of the brain region nodes; extracting spatio-temporal features of brain connections in the dynamic brain connection maps; inputting the spatio-temporal features into an abnormal connection detection network, calculating an abnormal probability of brain connections based on contrastive learning, and obtaining the brain connection with a highest abnormal probability at each time point; and generating the dynamic addictive neural circuit based on neuroscientific prior knowledge and the brain connection with the greatest probability of abnormality.