A tile spacing device and accompanying system and method are disclosed for spacing a plurality of tiles having a contour. In one embodiment of the tile spacing device, the tile spacing device includes a U-shaped band having a body with two branches extending parallel therefrom and an opening therebetween. An arm having a lateral end extends proximally from one of the branches into the opening. Two interlocking connectors are respectively positioned on the body at the opening and on the arm. In one embodiment of the system, two tile spacing devices complimentarily releasably mate when the tile spacing devices are opposing and perpendicularly displaced to interlock the interlocking connectors.