A preparation method of a polytetrafluoroethylene (PTFE)-based membrane for preventing and removing ices covering wind turbine blades is provided and the method comprises: preparing a membrane into a PTFE rod material with polymerized monomers by using monomer polymerization methods such as blending, pre-compressing and pushing; making the membrane into a PTFE-based homogeneous membrane with micropores and nano and micron scale concave-convex geometrical ultra-structure morphologies under the condition that the membrane is cracked to generate a laminar exfoliated fabric-like structure in the hot calendaring process of the PTFE rod material by using a hot calendaring and fusion polymerization method; and applying the PTFE-based homogeneous membrane to blades of a large wind turbine in operation.