A quick no-water startup apparatus for a centrifugal pump includes, from top to bottom in sequence, one-way passages (1), a self-priming chamber housing (41), sliding devices (5), a self-priming chamber (4), chamber partition plates (2) a concave-convex impeller (3), inlet channels (6) connected on two sides of the self-priming chamber (4), a spring device (7) of an upper-side x-shaped gas-liquid separation device, the upper-side x-shaped gas-liquid separation device (8), upper and middle-side gas-liquid separation device connecting shafts (9), a middle-side gas-liquid separation device (10), lower-side backflow-type gas-liquid separation devices (11), v-shaped backflow channels (122), an inverted v-shaped inlet channel (121), and an inlet. The quick no-water startup apparatus of the present invention enables the centrifugal pump to directly enter a normal operating condition after no-water startup, and 36 times of air exhaust can be completed while the concave-convex impeller (3) in the self-priming chamber (4) rotates by a circle in the early stage. Besides, the apparatus is provided with the upper, middle, and lower gas-liquid separation devices to fully realize separation of gas and liquid, so that gas can be exhausted more quickly and the chamber is filled with water. Therefore, the working efficiency is significantly improved and the operation process is greatly simplified.