- 专利标题: TL1A PATIENT SELECTION METHODS, SYSTEMS, AND DEVICES
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申请号: US18168519申请日: 2023-02-13
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公开(公告)号: US20230272061A1公开(公告)日: 2023-08-31
- 发明人: Laurens KRUIDENIER , Mahyar SABRIPOUR , Janine BILSBOROUGH , Dermot P. MCGOVERN , Dalin LI
- 申请人: PROMETHEUS BIOSCIENCES, INC. , CEDARS-SINAI MEDICAL CENTER
- 申请人地址: US CA San Diego
- 专利权人: PROMETHEUS BIOSCIENCES, INC.,CEDARS-SINAI MEDICAL CENTER
- 当前专利权人: PROMETHEUS BIOSCIENCES, INC.,CEDARS-SINAI MEDICAL CENTER
- 当前专利权人地址: US CA San Diego
- 主分类号: C07K16/24
- IPC分类号: C07K16/24 ; A61P1/04 ; C12Q1/6883 ; A61P1/00 ; C07K16/28
摘要:
Provided are methods, systems, and kits for selecting a patient for treatment with a therapeutic agent based on a presence of a genotype associated with a positive therapeutic response to the therapeutic agent. The therapeutic agent, in some embodiments, is an inhibitor of TL1A activity or expression, such as for example, an anti-TL1A antibody.
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