- 专利标题: CD20 BINDING MOLECULES AND USES THEREOF
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申请号: US18015690申请日: 2021-07-16
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公开(公告)号: US20230272104A1公开(公告)日: 2023-08-31
- 发明人: Xiaohu Fan , Zhe Zhou , Qiuchuan ZHUANG , Xu Fang , Hongbo PAN , Min Wei , Jianrui ZHU
- 申请人: Nanjing Legend Biotech Co., Ltd.
- 申请人地址: CN Nanjing
- 专利权人: Nanjing Legend Biotech Co., Ltd.
- 当前专利权人: Nanjing Legend Biotech Co., Ltd.
- 当前专利权人地址: CN Nanjing
- 优先权: WO TCN2020102463 2020.07.16
- 国际申请: PCT/CN2021/106886 2021.07.16
- 进入国家日期: 2023-01-11
- 主分类号: C07K16/28
- IPC分类号: C07K16/28 ; C07K14/725 ; A61P35/00
摘要:
The present disclosure provides single domain antibodies that bind to CD20, and chimeric antigen receptors comprising same. Further provided are engineered immune effector cells (such as T cells) comprising the chimeric antigen receptors. Pharmaceutical compositions, kits and methods of treating a disease or disorder are also provided.
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