A beverage bottle sealing assembly includes a beverage bottle that has a neck. A cap is removably engaged to the beverage bottle for closing the beverage bottle. An elongate panel is provided and the elongate panel is comprised of a non-adhesive material. A plurality of disks is each removably adhered to the elongate panel. A respective one of the disks is removable from the elongate panel and positioned over the beverage bottle when the cap has been removed from the beverage bottle. Furthermore, each of the disks is comprised of a compressible material thereby facilitating the disks to form a fluid impermeable seal between the beverage bottle and the cap. In this way the disk that is positioned on the beverage bottle retains freshness of a beverage contained in the beverage bottle.