Various embodiments disclosed relate to analyte sensor configurations. The present disclosure can include planar analyte sensors or coaxial analyte sensors. The planar analyte sensors can include one or more insulating and conductive layers and a substrate layered on each other. The coaxial analyte sensors can include one or more co-extruded wire electrodes with a substrate. The continuous analyte monitoring systems discussed herein can be configured to monitor one or more analytes to provide predictive and real-time health data and benefits.