Invention Publication
- Patent Title: N-CYANOPYRROLIDINES WITH ACTIVITY AS USP30 INHIBITORS
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Application No.: US18007641Application Date: 2021-06-03
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Publication No.: US20230303547A1Publication Date: 2023-09-28
- Inventor: Christopher Andrew LUCKHURST , Mark Ian KEMP , Paul William THOMPSON
- Applicant: MISSION THERAPEUTICS LIMITED
- Applicant Address: GB Cambridge
- Assignee: MISSION THERAPEUTICS LIMITED
- Current Assignee: MISSION THERAPEUTICS LIMITED
- Current Assignee Address: GB Cambridge
- Priority: GB 08401.8 2020.06.04 GB 16689.8 2020.10.21 GB 01935.1 2021.02.11
- International Application: PCT/EP2021/064897 2021.06.03
- Date entered country: 2022-12-01
- Main IPC: C07D413/12
- IPC: C07D413/12 ; A61P13/12 ; A61P19/04
Abstract:
The present invention relates to a class of N-cyanopyrrolidines with activity as inhibitors of the deubiquity lating enzyme USP30, having utility in a variety of therapeutic areas, including conditions involving mitochondrial dysfunction, cancer and fibrosis: (formulae (I)(i) and (I)(ii)).
Information query
