A method of equalization for high-speed processing and an equalizer thereof are proposed. The method of equalization includes determining a filter coefficient applied to a transmitter equalizer provided with a 2-tap precoder according to an approximate channel response characteristic, generating a pre-equalization signal by removing precursor ISI of a transmission feedback signal by the precoder to which the filter coefficient is applied, so as to output the pre-equalization signal as a transmitting signal, and receiving a transmission signal and generating an equalization signal by removing postcursor ISI of the received transmission signal by a receiver equalizer provided with a feedback filter having auxiliary coefficients for compensating for a difference between an overall channel response of the transmission signal and a channel response based on the precoder.