The present invention discloses a self-propelled cleaning machine of which a control module controls a driving device to prompt a dust compressing member mounted in a dust box to be at a compressing position or a non-compressing position. The dust compressing member of the self-propelled cleaning machine is capable of compressing trash in the dust box to keep the compressed trash within a specific space inside the dust box, thereby achieving an effect of reducing the number of times that a user has to clear the dust box.